NH2-C2-NH-Boc 是一种属于 ALKyl chain 类的 PROTAC linker,可用于 PROTAC 分子的合成。
产品描述
NH2-C2-NH-Boc (PROTAC Linker 22) is a alkyl chain-based PROTAC linker. NH2-C2-NH-Boc can be used in the synthesis of PROTACs.
体外活性
PROTACs contain two different ligands connected by a linker; one of them is a ligand for an E3 ubiquitin ligase and the other one is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
Cas No.
57260-73-8
分子式
C7H16N2O2
分子量
160.21
别名
N-叔丁氧羰基-1,2-乙二胺;PROTAC Linker 22;NH2-C2-NH-Boc
储存和溶解度
DMSO:10 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years