6-MaleimIDOcapronic acid 是一种属于 ALKyl chain 类的 PROTAC linker,可用于 PROTAC 分子的合成。
产品描述
6-Maleimidocapronic acid is an alkyl chain-based PROTAC linker that can be used in PROTAC synthesis.
体外活性
PROTACs contain two different ligands connected by a linker; one of them is a ligand for an E3 ubiquitin ligase and the other one is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
Cas No.
55750-53-3
分子式
C10H13NO4
分子量
211.21
别名
6-Maleimidocapronic acid
储存和溶解度
DMSO:190 mg/mL (899.58 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years