m-PEG7-4-nitrophenyl carbonate 是一种属于 PEG 类的 PROTAC linker,可用于 PROTAC 分子的合成。
产品描述
m-PEG7-4-nitrophenyl carbonate is a PEG-based PROTAC linker that can be used in PROTAC synthesis[1].
体外活性
PROTACs contain two different ligands connected by a linker; one of them is a ligand for an E3 ubiquitin ligase and the other one is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
Cas No.
678150-56-6
分子式
C20H31NO11
分子量
461.46
别名
m-PEG7-4-nitrophenyl carbonate
储存和溶解度
DMSO:10 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years