Bromo-PEG2-CH2-Boc 是一种属于 PEG 类的 PROTAC linker,可用于 PROTAC 分子的合成。
产品描述
Bromo-PEG2-CH2-Boc is a PEG-based PROTAC linker that can be used in PROTAC synthesis[1].
体外活性
PROTACs contain two different ligands connected by a linker; one of them is a ligand for an E3 ubiquitin ligase and the other one is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
Cas No.
1807518-63-3
分子式
C10H19BrO4
分子量
283.16
别名
乙酸叔丁酯-二聚乙二醇-溴代;Bromo-PEG2-CH2-Boc
储存和溶解度
DMSO:10 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years