Broad spectrum neuropeptide inverse agonist and antagonist. Potent full inverse agonist for the ghrelin receptor (EC50 = 5.2 nM); diminishes constitutive ghrelin receptor signaling. Also antagonist at tachykinin, bradykinin, CCK and bombesin receptors. Induces apoptosis and inhibits cancer cell growth in vitro.

96736-12-8

C79H109N19O12

1516.85

[D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P

H2O:1 mg/mL
Powder: -20°C for 3 years
In solvent: -80°C for 2 years