AKAP disruptor. Selectively binds PKA-RI with high affinity (KD values are 6.2 and 12.1 nM for the RIα and β subunits, respectively) and blocks its interaction with AKAP. Inhibits type I PKA-mediated phosphorylation in live cells. Cell permeable.

TP2129

C109H181N25O35

2401.75

RI-STAD 2

50% acetonitrile / water:1 mg/mL
Powder: -20°C for 3 years
In solvent: -80°C for 2 years