您好,欢迎来到化工原料网! [登录] [免费注册]
化工原料网
位置:首页 > 产品库 > Cdk2/Cyclin Inhibitory Peptide I
立即咨询
咨询类型:
     
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
 
Cdk2/Cyclin Inhibitory Peptide I
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Cdk2/Cyclin Inhibitory Peptide I图片
包装与价格:
包装价格(元)
1 mg电议
5 mg电议
10 mg电议
25 mg电议

产品介绍

产品描述

Cyclin-dependent kinase 2 also known as cell division protein kinase 2. The protein encoded by this gene is a member of the cyclin-dependent kinase family of Ser/Thr protein kinases. This protein kinase is highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2, also known as Cdk1 in humans.

体外活性

It is a catalytic subunit of the cyclin-dependent kinase complex, whose activity is restricted to the G1-S phase of the cell cycle and is essential for the G1/S transition. This protein associate with and is regulated by the regulatory subunits of the complex including cyclin E or A. Cyclin E binds G1 phase Cdk2, which is required for the transition from G1 to S phase while binding with Cyclin A is required to progress through the S phase. Its activity is also regulated by phosphorylation. Two alternatively spliced variants and multiple transcription initiation sites of this gene have been reported. The role of this protein in the G1-S transition has been recently questioned as cells lacking Cdk2 are reported to have no problem during this transition [2][3].

Cas No.

TP2192

分子式

C111H196N48O23

分子量

2571.05

别名

Cdk2/Cyclin Inhibitory Peptide I

储存和溶解度

DMSO:≥257.1mg/mL
Powder: -20°C for 3 years
In solvent: -80°C for 2 years