产品描述
HS-PEG7-CH2CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
体外活性
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
Cas No.
T18027
分子式
C17H34O9S
分子量
414.51
别名
Thiol-PEG7-propionic acid;HS-PEG7-CH2CH2COOH
储存和溶解度
(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years