Potent human MC1 receptor antagonist (IC50 = 17 nM). Also partial agonist at human MC3 and MC5 receptors (EC50 values are 59 and 1300 nM, respectively). Exhibits binding affinity for A375 melanoma cells in vitro. Reverses morphine-induced hyperalgesia in female mice, with no effect in male mice. γMSH analog.

1416983-77-1

C62H82N20O13S

1347.51

MSG 606;MSG606

H2O:1 mg/mL
Powder: -20°C for 3 years
In solvent: -80°C for 2 years