TLR4-IN-C34 is an orally bioavailable TLR4 inhibitor and reduces systemic inflammation in models of endotoxemia and necrotizing enterocolitis. References: [1]. Neal MD, et al. Discovery and validation of a new class of small molecule Toll-like receptor 4 (TLR4) inhibitors. PLoS One. 2013 Jun 12;8(6):e65779.
[2]. Wipf P, et al. Synthesis of anti-inflammatory α-and β-linked acetamidopyranosides as inhibitors of toll-like receptor 4 (TLR4). Tetrahedron Lett. 2015 Jun 3;56(23):3097-3100.
纯度:≥98%
CAS:40592-88-9