Indomethacin-D4 (Indometacin-D4) is a deuterated form of Indomethacin. Indomethacin is a highly potent and nonspecific inhibitor of COX1 and COX2, with IC50s of 18 nM and 26 nM for human COX-1 and COX-2, respectively, in CHO cells. References: [1]. Riendeau D, et al. Biochemical and pharmacological profile of a tetrasubstituted furanone as a highly selective COX-2 inhibitor. Br J Pharmacol. 1997 May;121(1):105-17.

纯度：≥98%

CAS：87377-08-0