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ROS 234 dioxalate
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
CAS NO:1781941-93-2
包装:50mg, 100mg, 250mg
规格:≥98%

产品介绍

ROS 234 dioxalate is a highly potent H3 antagonist, with a pKB of 9.46 for Guinea-pig ileum H3-receptor, a pKi of 8.90 for Rat cerebral cortex H3-receptor, and a ED50 of 19.12 mg/kg (ip) in ex vivo of Rat cerebral cortex. ROS 234 dioxalate diaplays poor central access. References: [1]. Ballabeni V, et al. CNS access of selected H3-antagonists: ex vivo binding study in rats. Inflamm Res. 2002 Apr;51 Suppl 1:S55-6. [2]. Mor M, et al. Synthesis, biological activity, QSAR and QSPR study of 2-aminobenzimidazole derivatives as potent H3-antagonists. Bioorg Med Chem. 2004 Feb 15;12(4):663-74.

纯度:≥98%

CAS:1781941-93-2