18-Oxocortisol is a derivative of cortisol that is produced by aldosterone synthase (CYP11B2). 18-Oxocortisol is a naturally occurring mineralocorticoid agonist. 18-Oxocortisol is a biomarker in adrenal vein sampling. References: [1]. Nakamura Y, et al. 18-oxocortisol measurement in adrenal vein sampling as a biomarker for subclassifying primaryaldosteronism. J Clin Endocrinol Metab. 2011 Aug;96(8):E1272-8.
[2]. Ulick S, et al. 18-oxocortisol, a naturally occurring mineralocorticoid agonist. Endocrinology. 1983 Dec;113(6):2320-2.
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CAS:2410-60-8