RO3280(PLK1 抑制剂,1062243-51-9 )也称为 Ro5203280,是一种有效的选择性 PLK 1 抑制剂,具有出色的体外细胞效力。Ro3280 (1062243-51-9)is an effective, specific inhibitor of PLK1(IC50=3, Kd=0.09 nM).
中文别名 | RO3280; RO-3280; RO 3280; Ro5203280; Ro-5203280; Ro 5203280;PLK1抑制剂;PLK1 抑制剂 |
英文别名 | Ro3280;PLK1 inhibitor |
CAS号 | 1062243-51-9 |
SMILES | O=C(NC1CCN(C)CC1)C2=CC=C(NC3=NC=C(N4C)C(N(C5CCCC5)CC(F)(F)C4=O)=N3)C(OC)=C2 |
Inchi | InChI=1S/C27H35F2N7O3/c1-34-12-10-18(11-13-34)31-24(37)17-8-9-20(22(14-17)39-3)32-26-30-15-21-23(33-26)36(19-6-4-5-7-19)16-27(28,29)25(38)35(21)2/h8-9,14-15,18-19H,4-7,10-13,16H2,1-3H3,(H,31,37)(H,30,32,33) |
InchiKey | DJNZZLZKAXGMMC-UHFFFAOYSA-N |
分子式 Formula | C27H35F2N7O3 |
分子量 Molecular Weight | 543.61 |
性状 | Solid power |
储藏条件 Storage conditions | 0 - 4 C for short term (days to weeks), or -20 C for long term (months). |