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SHR-0302
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
SHR-0302图片
CAS NO:1445987-21-2
规格:≥98%
包装与价格:
包装价格(元)
5mg电议
10mg电议
25mg电议
50mg电议
100mg电议
250mg电议

产品介绍

SHR0302 (SHR-0302) is a novel, highly potent and orally bioavailable inhibitor of the JAK family kinases, with high selectivity for JAK1 and has potent anti-inflammatory and anticancer effects. The selectivity of SHR0302 for JAK1 is >10-fold for JAK2, 77-fold for JAK3, 420-fold for Tyk2. SHR0302 inhibits JAK1-STAT3 phosphorylation and induces the apoptosis of hepatic stellate cells. SHR0302 has anti-proliferative and anti-inflammatory effects by blocking JAK/STAT3 signaling, suppressing proliferation, migration and collagen production, and inducing the apoptosis of hepatic stellate cells.

纯度:≥98%

CAS:1445987-21-2