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Uridine 5'-diphosphate sodium salt
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
CAS NO:21931-53-3
包装:50mg, 100mg, 250mg
规格:≥98%

产品介绍

Uridine 5'-diphosphate sodium salt is a highly potent, specific P2Y6 receptor native agonist (EC50=300 nM; pEC50=6.52) and a highly potent P2Y14 antagonist (pEC50=7.28). Uridine 5'-diphosphate sodium salt, an endogenous metabolite, catalyzes the glucuronidation of a wide array of substrates and is used in nucleic acid (RNA) biosynthesis. References: [1]. Jacobson KA, et al. Development of selective agonists and antagonists of P2Y receptors. Purinergic Signal. 2009 Mar;5(1):75-89. [2]. Kim B, et al. Uridine 5'-diphosphate induces chemokine expression in microglia and astrocytes through activation of the P2Y6 receptor. J Immunol. 2011 Mar 15;186(6):3701-9.

纯度:≥98%

CAS:21931-53-3