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Axitinib sulfoxide(AG028458 PF03482595)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Axitinib sulfoxide(AG028458 PF03482595)图片
CAS NO:1347304-18-0
规格:≥98%
包装与价格:
包装价格(元)
5mg电议
10mg电议
25mg电议
50mg电议

产品介绍

Axitinib sulfoxide (also known as AG-028458; PF-03482595) is a primary and S-oxidized metabolite of Axitinib, an investigational anticancer drug. Axitinib (AG013736 and Inlyta) is a potent, orally bioavailable, small molecule and multi-targeted inhibitor TKI (tyrosine kinase inhibitor) that inhibits VEGFR1, VEGFR2, VEGFR3, PDGFRβ and c-Kit with IC50 of 0.1 nM, 0.2 nM, 0.1-0.3 nM, 1.6 nM and 1.7 nM in Porcine aorta endothelial cells, respectively.

纯度:≥98%

CAS:1347304-18-0