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VU0134992 HCl
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
CAS NO:1052515-91-9
包装:50mg, 100mg, 250mg
规格:≥98%

产品介绍

VU0134992 HCl is the first subtype-preferring, orally bioavailable and specific Kir4.1 potassium channel pore blocker, with an IC50 of 0.97 μM. VU0134992 HCl is 9-fold specific for homomeric Kir4.1 over Kir4.1/5.1 concatemeric channels (IC50=9 μM) at -120 mV. References: [1]. Kharade SV, et al. Discovery, Characterization, and Effects on Renal Fluid and Electrolyte Excretion of the Kir4.1 Potassium Channel Pore Blocker, VU0134992. Mol Pharmacol. 2018 Aug;94(2):926-937.

纯度:≥98%

CAS:1052515-91-9