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WAY-181187(SAX-187)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
WAY-181187(SAX-187)图片
CAS NO:554403-49-5
规格:≥98%
包装与价格:
包装价格(元)
5mg电议
10mg电议
25mg电议
50mg电议
100mg电议
250mg电议
500mg电议

产品介绍

WAY-181187 (SAX187) is a novel, potent and selective 5-HT6 receptor agonist with a Ki of 2.2 nM and an EC50 of 6.6 nM. WAY-181187 possesses high affinity binding (2.2 and 4.8 nM, respectively) at the human 5-HT6 receptor and profile as full receptor agonists (WAY- EC50=6.6 nM, Emax=93%). In the rat frontal cortex, acute administration of WAY-181187 (3-30 mg/kg, subcutaneous (s.c.)) significantly increased extracellular GABA concentrations without altering the levels of glutamate or norepinephrine.

纯度:≥98%

CAS:554403-49-5