Desethyl chloroquine is a primary N-deethylated (removal of an ethyl group) metabolite of Chloroquine by CYP2C8 and CYP3A4, inhibiings the growth of the P. falciparum strain LA136 in vitro. Chloroquine diphosphate is an inhibitor of autophagy and toll-like receptors (TLRs). Desethyl chloroquine possesses antiplasmodic activity.
纯度:≥98%
CAS:1476-52-4