LpxH-IN-AZ1, a sulfonyl piperazine compound, is a highly potent UDP-2,3-diacylglucosamine pyrophosphate hydrolase LpxH inhibitor. LpxH-IN-AZ1 is a highly potent inhibitor of Klebsiella pneumoniae LpxH with IC50 of 0.36 μM . References: [1]. Cho J, et al. Structural basis of the UDP-diacylglucosamine pyrophosphohydrolase LpxH inhibition by sulfonyl piperazine antibiotics. Proc Natl Acad Sci U S A. 2020 Feb 25;117(8):4109-4116.

纯度：≥98%

CAS：901260-40-0