DB1976 (DB-1976), a selenophene analog of DB270, is a novel and potent transcription factor PU.1 inhibitor with apoptosis-inducing activity. It inhibits PU.1 binding (IC50 = 10 nM) and strongly inhibits the PU.1/DNA complex (with high DB1976-λB affinity, KD = 12 nM).
纯度:≥98%
CAS:1557397-51-9