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Rovatirelin(S0373)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Rovatirelin(S0373)图片
CAS NO:204386-76-5
规格:≥98%
包装与价格:
包装价格(元)
50mg电议
100mg电议
250mg电议

产品介绍
Rovatirelin (S-0373) is a novel, synthetic and non-peptide mimetic of thyrotropin-releasing hormone (TRH) being developed by Kissei Pharmaceutical for the treatment of spinocerebellar degeneration. Rovatirelin binds to the human TRH receptor with higher affinity (Ki=702nM) than taltirelin (Ki=3877nM). Rovatirelin increased the spontaneous firing of action potentials in the acutely isolated noradrenergic neurons of rat locus coeruleus (LC). Rovatirelin increased locomotor activity. Rovatirelin may have an orally effective therapeutic potential in patients with SCD.