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OTS186935 triHCl
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
CAS NO:2093401-85-3
包装:50mg, 100mg, 250mg
规格:≥98%

产品介绍

OTS186935 triHCl is a protein methyltransferase SUV39H2 inhibitor with an IC50 of 6.49 nM. OTS186935 triHCl shows significant inhibition of tumor growth in mouse xenograft models without any detectable toxicity. OTS186935 triHCl regulates the production of γ-H2AX in cancer cells. References: [1]. Vougiouklakis T, et al. Development of novel SUV39H2 inhibitors that exhibit growth suppressive effects in mouse xenograft models and regulate the phosphorylation of H2AX. Oncotarget. 2018 Aug 7;9(61):31820-31831.

纯度:≥98%

CAS:2093401-85-3