您好,欢迎来到化工原料网! [登录] [免费注册]
化工原料网
位置:首页 > 产品库 > Vatalanib(PTK-787 ZK-222584 CGP-79787)
立即咨询
咨询类型:
     
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
 
Vatalanib(PTK-787 ZK-222584 CGP-79787)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Vatalanib(PTK-787 ZK-222584 CGP-79787)图片
CAS NO:212141-54-3
规格:≥98%
包装与价格:
包装价格(元)
5mg电议
10mg电议
25mg电议
50mg电议
100mg电议
250mg电议
500mg电议
1g电议

产品介绍

Vatalanib ((PTK787 or ZK 222584, cpg-79787) is a novel, potent and orally bioavailable inhibitor of VEGFR2/KDR with IC50 of 37 nM in a cell-free assay, it is less potent against VEGFR1/Flt-1, and is 18-fold against VEGFR3/Flt-4. It is an anilinophthalazine analog with potential antineoplastic activity. Vatalanib binds to and inhibits the protein kinase domain of VEGFR 1 and 2. This agent also binds to and inhibits related receptor tyrosine kinases, including PDGF receptor, c-Kit, and c-Fms.

纯度:≥98%

CAS:212141-54-3