Description: Lobeline sulfate, an alkaloid and nonstimulant medication that can alter dopamine uptake in brain, is a novel and potent a nicotinic receptor agonist and VMAT2 ligand, which stimulates dopamine release, and inhibits the reuptake of dopamine and serotonin, acting as a mixed agonist-antagonist at nicotinic acetylcholine receptors and antagonist at μ-opioid receptors.
Related CAS: 134-63-4 (HCl); 90-69-7 (free); 246018-80-4 (Lobeline, (+)-); 134-64-5 (sulfate)