ML132 (NCGC 00185682，1230628-71-3)是有效和选择性的 caspase 1 抑制剂，IC
50 值为 0.316 nM
| 中文别名 | ML132(cas:1230628-71-3) |
| 英文别名 | ML132,1230628-71-3,ML-132; ML132; CID-4462093; CID 4462093; CID4462093; NCGC-00183434; NCGC 00183434; NCGC00183434 |
| CAS号 | 1230628-71-3 |
| SMILES | ClC1=CC(C(N[C@@H](C(C)(C)C)C(N2CCC[C@H]2C(N[C@@H](CC(O)=O)C#N)=O)=O)=O)=CC=C1N |
| Inchi | InChI=1S/C22H28ClN5O5/c1-22(2,3)18(27-19(31)12-6-7-15(25)14(23)9-12)21(33)28-8-4-5-16(28)20(32)26-13(11-24)10-17(29)30/h6-7,9,13,16,18H,4-5,8,10,25H2,1-3H3,(H,26,32)(H,27,31)(H,29,30)/t13-,16-,18+/m0/s1 |
| InchiKey | KENKPOUHXLJLEY-QANKJYHBSA-N |
| 分子式 Formula | C22H28ClN5O5 |
| 分子量 Molecular Weight | 477.94 |
| 闪点 FP | 428.9±32.9 ℃ |
| 沸点 Boiling point | 785.6±60.0 ℃ at 760 mmHg |
| Polarizability极化度 | 47.6±0.5 10-24cm3 |
| 密度 Density | 1.3±0.1 g/cm3 |
| 蒸汽压 Vapor Pressure | 0.0±2.9 mmHg at 25℃ |
| 性状 | Solid |
| 储藏条件 Storage conditions | 请根据产品建议的存储条件进行存储,Please store the product under the recommended condition sin the description. |
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