24R-Calcipotriol (PRI 2202; Impurity D of Calcipotriol) is an impurity of Calcipotriol; Calcipotriol is a synthetic calcitriol/Vitamin D3 (VD3) analog and an agonist of the
VD3 receptor. It is used in the treatment of psoriasis and marketed
under the trade name Dovonex. It has comparable affinity with calcitriol
(Vit. D) for the Vitamin D receptor (VDR), while being less than 1% as
active as the calcitriol in regulating calcium metabolism. Chronic
plaque psoriasis is the chief medical use of calcipotriol. It has also
been used successfully in the treatment of alopecia areata.
纯度:≥98%
CAS:112827-99-3