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GsMTx4 TFA
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
GsMTx4 TFA图片
CAS NO:1209500-46-8
规格:≥98%
包装与价格:
包装价格(元)
1mg电议
2mg电议
5mg电议
10mg电议

产品介绍

GsMTx4, a TRPC1 and TRPC6 blocker, is a naturally occuring spider venom peptide composed of 34 amino acids, isolated from the Grammostola rosea (Chilean rose) tarantula venom and belongs to the huwentoxin-1 family. It selectively inhibits cation-permeable mechanosensitive channels (MSCs) belonging to the Piezo and TRP channel families. GsMTx4 is an important pharmacological tool for identifying the role of these excitatory MSCs in normal physiology and pathology. GsMTx4 significantly attenuates bladder hyperactivity. Also blocks stretch-activated cation channels in astrocytes, cardiac cells, and smooth and skeletal muscle cells. Also inhibits TACAN, a mechanosensitive ion channel involved in the pain response.

纯度:≥98%

CAS:1209500-46-8