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Doxercalciferol Impurity
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Doxercalciferol Impurity图片
CAS NO:127516-23-8
规格:≥98%
包装与价格:
包装价格(元)
2mg电议
5mg电议
10mg电议
25mg电议

产品介绍

Doxercalciferol Impurity is a major impurity of doxercalciferol, which is a synthetic analog of vitamin D2 and a potent activator of Vitamin D receptor with important biological activities. It suppresses parathyroid synthesis and secretion, and has been used to treat secondary hyperparathyroidism and metabolic bone disease. Doxercalciferol (100 or 300 pg/g b.w.) normalizes serum calcium and parathyroid hormone (PTH) levels in nephrectomy treated mice. Doxercalciferol (300 pg/g b.w.) significantly reduces osteitis fibrosa in nephrectomy treated mice. Doxercalciferol results in significant decrease in cardiac hypertrophy and improves cardiac function in rats fed a high salt (HS) diet. Doxercalciferol treatment leads to a significant decrease in plasma brain natriuretic peptide (BNP) level and tissue atrial natriuretic factor (ANF) mRNA level in rats fed a high salt (HS) diet.

纯度:≥98%

CAS:127516-23-8