Seocalcitol (EB-1089) is a novel second generation vitamin D analog with potential antineoplastic activity. It binds to vitamin D receptor protein from human osteosarcoma MG-63 cells with Kd of 0.27 nM. Seocalcitol binds to and activates the vitamin D receptor, a cytoplasmic polypeptide expressed in normal vitamin D responsive tissues, but also overexpressed in certain cancers including hepatocellular carcinoma and pancreatic cancer.

纯度：≥98%

CAS：134404-52-7