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KP-457
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
KP-457图片
CAS NO:1365803-52-6
规格:≥98%
包装与价格:
包装价格(元)
5mg电议
10mg电议
25mg电议
50mg电议

产品介绍
KP-457 (KP457) is a novel, potent and selective inhibitor of disintegrin and metalloproteinase 17 (ADAM17) with potential usefulness in Cardiovascular Disease. It has higher selectivity for ADAM17 than for other MMPs and ADAM10, and IC50s are 11.1 nM (ADAM17), 748 nM (ADAM10), 717 nM (MMP2), 9760 nM (MMP3), 2200 nM (MMP8), 5410 nM (MMP9), 930 nM (MMP13), 2140 nM (MMP14), and 7100 nM (MMP17), respectively.
理化性质和储存条件

Molecular Formula: C21H24N2O7S2;

Molecular Weight: 480.55;

Synonym: KP457; KP 457; KP-457

SMILES: CS(=O)(NCC1=CC=C(C(N(C=O)O)CS(=O)(C2=CC=C(OCC#CC)C=C2)=O)C=C1)=O