NE 52-QQ57 is a selective, and orally bioavailable GPR4 antagonist with an IC50 of 70 nM. Anti-inflammatory activities. References: Velcicky J, et al. Development of Selective, Orally Active GPR4 Antagonists with Modulatory Effects on Nociception, Inflammation, and Angiogenesis. J Med Chem. 2017 May 11;60(9):3672-3683. [2]. Hosford PS, et al. CNS distribution, signalling properties and central effects of G-protein coupled receptor 4. Neuropharmacology. 2018 Aug;138:381-392.

纯度：≥98%

CAS：1401728-56-0