VXc-486 (SPR-719) is a novel and potent gyrase B inhibitor with high bactericidal activity and the potential for treatment of tuberculosis and nontuberculosis mycobacterial infections. VXc-486 potently inhibits multiple drug-sensitive isolates and drug-resistant isolates of Mycobacterium tuberculosis, with MICs of 0.03 to 0.30 μg/ml and 0.08 to 5.48 μg/ml, respectively.
纯度:≥98%
CAS:1384984-18-2