GSK3368715 (GSK-3368715; EPZ-019997; EPZ019997) is a novel, orally bioactive, and reversible inhibitor of type I PRMTs (protein arginine methyltransferases) with potential antitumor activity. It inhibits PRMT1/3/4/6/8 with IC50s of 3.1
nM, 48 nM, 1148 nM, 5.7 nM, 1.7 nM, respectively.