BQ788 is a novel, potent and selective
ETB (endothelin B) receptor antagonist, attenuating stab wound
injury-induced reactive astrocytes in rat brain and inhibiting ET-1
binding to ETB receptors with an IC50 of 1.2 nM in human Girrardi heart
cells. BQ788 were well tolerated and showed signs of directly and
indirectly reducing the viability of melanoma cells.
纯度:≥98%
CAS:173326-37-9