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Nepicastat(SYN117 and RS25560-197)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Nepicastat(SYN117 and RS25560-197)图片
CAS NO:173997-05-2
规格:≥98%
包装与价格:
包装价格(元)
25mg电议
50mg电议
100mg电议
250mg电议
500mg电议

产品介绍

Description: Nepicastat (SYN-117 and RS-25560-197) is a potent and selective inhibitor of both bovine and human dopamine-β-hydroxylase with IC50 of 8.5 nM and 9 nM, with negligible affinity for twelve other enzymes and thirteen neurotransmitter receptors. Dopamine beta-hydroxylase is an enzyme that catalyzes the conversion of dopamine to norepinephrine.Nepicastat has been studied as a possible treatment for congestive heart failure, and appears to be well tolerated.

References: Br J Pharmacol. 1997 Aug;121(8):1803-9; J Cardiovasc Pharmacol. 1998 Jun;31(6):963-70.

Related CAS #: 170151-24-3 (HCl); 173997-05-2 (free base); 195881-94-8 (HCl R isomer)

纯度:≥98%

CAS:173997-05-2