OSMI-4 is a novel and potent inhibitor of O-GlcNAc transferase (OGT) with an EC50 of ~3 μM in cells. It reduces O-GlcNAc levels almost completely by 5 μM (O-GlcNAc (RL-2) blot of HEK293T cell lysates after treatment); OSMI-4 is the best OGT inhibitor reported to date, and it is especially attractive for probing OGT’s complex biology.
纯度:≥98%
CAS:2260791-14-6