Tinidazole is an antiprotozoal, antibacterial agent. The nitro- group of tinidazole is reduced by cell extracts of Trichomonas. The free nitro- radical generated as a result of this reduction may be responsible for the antiprotozoal activity. Chemically reduced tinidazole was shown to release nitrites and cause damage to purified bacterial DNA in vitro. Additionally, the drug caused DNA base changes in bacterial cells and DNA strand breakage in mammalian cells. The mechanism by which tinidazole exhibits activity against Giardia and Entamoeba species is not known. References: Escobedo AA, Ballesteros J, González-Fraile E, Almirall P. A meta-analysis of the efficacy of albendazole compared with tinidazole as treatments for Giardia infections in children. Acta Trop. 2016 Jan;153:120-7. doi: 10.1016/j.actatropica.2015.09.023. Epub 2015 Oct 22. Review. PubMed PMID: 26476393.

纯度：≥98%

CAS：19387-91-8