Pumiliotoxins (PTXs), are one of several toxins found in the skin of poison dart frogs. There are three different types of A, B and C, of which toxins A and B are more toxic than C. Pumiliotoxins interfere with muscle contraction by affecting calcium channels, causing partial paralysis, difficulty moving, hyperactivity, or death. References: Qu J, Helmchen G. Applications of Iridium-Catalyzed Asymmetric Allylic Substitution Reactions in Target-Oriented Synthesis. Acc Chem Res. 2017 Oct 17;50(10):2539-2555. doi: 10.1021/acs.accounts.7b00300. Epub 2017 Sep 22. PubMed PMID: 28937739.
纯度:≥98%
CAS:27766-71-8