CAS NO: | 6429-04-5 |
规格: | ≥98% |
包装 | 价格(元) |
5g | 电议 |
10g | 电议 |
25g | 电议 |
50g | 电议 |
Molecular Weight (MW) | 379.88 |
---|---|
Formula | C20H25NO4.HCl |
CAS No. | 6429-04-5 |
Storage | -20℃ for 3 years in powder form |
-80℃ for 2 years in solvent | |
Solubility (In vitro) | DMSO: 76 mg/mL (200.1 mM) |
Water: <1 mg/mL | |
Ethanol: 7 mg/mL (18.4 mM) | |
SMILES Code | COC1=C(C=C(C=C1)CC2C3=CC(=C(C=C3CCN2)OC)OC)OC.Cl |
Synonyms | Norlaudanosine HCl; Tetrahydropapaverine |
In Vitro | In vitro activity: Tetrahydropapaverine, one of the TIQs and an analogue of salsolinol and tetrahydropapaveroline, has been reported to have neurotoxic effects on dopamine neurons. Tetrahydropapaverine inhibits serotonin biosynthesis in serotonin-producing murine mastocytoma P815 cells with an IC50 of 7.5 μM and reduces tryptophan hydroxylase activity with an IC50 of 5.7 μM. |
---|---|
In Vivo | |
Animal model | |
Formulation & Dosage | |
References | Life Sci. 2004 Sep 3;75(16):1949-57; Brain Res. 1997 Apr 18;754(1-2):260-8. |