您好,欢迎来到化工原料网! [登录] [免费注册]
化工原料网
位置:首页 > 产品库 > Tetrahydropapaverine HCl
立即咨询
咨询类型:
     
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
 
Tetrahydropapaverine HCl
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Tetrahydropapaverine HCl图片
CAS NO:6429-04-5
规格:≥98%
包装与价格:
包装价格(元)
5g电议
10g电议
25g电议
50g电议

产品介绍
理化性质和储存条件
Molecular Weight (MW)379.88
FormulaC20H25NO4.HCl
CAS No.6429-04-5
Storage-20℃ for 3 years in powder form
-80℃ for 2 years in solvent
Solubility (In vitro)DMSO: 76 mg/mL (200.1 mM)
Water: <1 mg/mL
Ethanol: 7 mg/mL (18.4 mM)
SMILES CodeCOC1=C(C=C(C=C1)CC2C3=CC(=C(C=C3CCN2)OC)OC)OC.Cl
SynonymsNorlaudanosine HCl; Tetrahydropapaverine
实验参考方法
In Vitro

In vitro activity: Tetrahydropapaverine, one of the TIQs and an analogue of salsolinol and tetrahydropapaveroline, has been reported to have neurotoxic effects on dopamine neurons. Tetrahydropapaverine inhibits serotonin biosynthesis in serotonin-producing murine mastocytoma P815 cells with an IC50 of 7.5 μM and reduces tryptophan hydroxylase activity with an IC50 of 5.7 μM.

In Vivo
Animal model
Formulation & Dosage
References

Life Sci. 2004 Sep 3;75(16):1949-57; Brain Res. 1997 Apr 18;754(1-2):260-8.