3-Hydroxy-4-methoxycinnamic acid (Isoferulic acid) is a cinnamic acid analogue that has antidiabetic activity. 3-Hydroxy-4-methoxycinnamic acid binds to and activates α1-adrenergic receptors (IC50=1.4 μM) to enhance secretion of β-endorphin (EC50=52.2 nM) and increase glucose use. References: Liu IM, et al. Mediation of beta-endorphin by isoferulic acid to lower plasma glucose in streptozotocin-induced diabetic rats. J Pharmacol Exp Ther. 2003 Dec;307(3):1196-204.
纯度:≥98%
CAS:537-73-5