BMS-199264 hydrochloride is a novel and potent inhibitor of the ATP hydrolase activity of mitochondrial F1F0 ATP synthase. It has no affect on the ATP synthase function of F1F0. In isolated rat hearts, BMS-199624 blocks depletion of ATP levels, and blocks necrosis during ischemia. BMS-191264 decreases cardiac necrosis and improves the recovery of contractile activities after reperfusion.
纯度:≥98%
CAS:186180-83-6