Description: Quinine HCl is a naturally occuring and white crystalline K+ channel blocker used to treat malaria, also has antipyretic (fever-reducing), analgesic (painkilling), anti-inflammatory properties and a bitter taste. It is a stereoisomer of of quinidine which contains an aromatic quinoline and a bicyclic quinuclidine. Quinine prevents formation of tumor necrosis factor (TNF) as well as the subsequent hepatic DNA fragmentation and liver enzyme leakage. Quinine elicits Fos-like immunoreactivity (FLI) concentrated in the medial third of the nucleus.
References: Proc Natl Acad Sci U S A. 2001 Sep 11;98(19):10942-7; Eur J Pharmacol. 1995 Dec 27;294(1):353-5.
Related CAS #: 6119-47-7 (QuinineHCl dihydrate) 130-95-0 (Quinine free base) 60-93-5 (2HCl) 6119-70-6 (sulfate dihydrate) 804-63-7 (sulfate) 549-49-5 (HBr)