20-HETE (20-hydroxy Arachidonic Acid), a vasoconstrictor produced in vascular smooth muscle (VSM) cells, is a lipid mediator which activates the transcription of ACE via NFkB translocation and promoter binding. It is also a CYP450 metabolite and a potent vasoconstrictor. This causes detrimental effects in cerebral circulation, and modulating KCa3.1 channels.
纯度:≥98%
CAS:79551-86-3