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BG45
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
BG45图片
CAS NO:926259-99-6
包装与价格:
包装价格(元)
10mg电议
5mg电议

产品介绍

BG45(cas:926259-99-6) is a potent and selective HDAC3 inhibitor inhibitor with selectivity for HDAC3 (IC50 = 289 nM) over HDAC1, 2. BG45 did not inihibit HDAC6. BG45 signigicantly inhibited tumor growth in a mouse model of multiple myeloma either alone and synergistically in combination with bortezomib. HDAC3 represents a promising therapeutic target, and validate a prototype novel HDAC3 inhibitor BG45 in MM.
中文别名BG45(cas:926259-99-6);HDAC3 inhibitor;HDAC3抑制剂
英文别名BG45,926259-99-6
CAS号926259-99-6
SMILESO=C(C1=NC=CN=C1)NC2=CC=CC=C2N
InchiInChI=1S/C11H10N4O/c12-8-3-1-2-4-9(8)15-11(16)10-7-13-5-6-14-10/h1-7H,12H2,(H,15,16)
InchiKeyLMWPVSNHKACEKW-UHFFFAOYSA-N
分子式 FormulaC11H10N4O
分子量 Molecular Weight214.22
闪点 FP146.7±25.1 ℃
沸点 Boiling point319.0±32.0 ℃ at 760 mmHg
Polarizability极化度24.3±0.5 10-24cm3
密度 Density1.4±0.1 g/cm3
蒸汽压 Vapor Pressure0.0±0.7 mmHg at 25℃
溶解度SolubilityDMSO (Slightly), Methanol (Slightly)
性状固体粉末,Power
储藏条件 Storage conditions-20℃ 3 years年 4℃ 2 years年 / In solvent溶液中:-80℃ 6 months月 -20℃ 1 month月