ORM-10962 is a potent, highly selective sodium-calcium exchanger (NCX) inhibitor, with IC50 of 67 and 55 nM for the reverse and forward mode inhibition, respectively. References: Kohajda Z, et al. The Effect of a Novel Highly Selective Inhibitor of the Sodium/Calcium Exchanger (NCX) on Cardiac Arrhythmias in In Vitro and In Vivo Experiments. PLoS One. 2016 Nov 10;11(11):e0166041. [2]. Oravecz K, et al. Inotropic effect of NCX inhibition depends on the relative activity of the reverse NCX assessed by a novel inhibitor ORM-10962 on canine ventricular myocytes. Eur J Pharmacol. 2018 Jan 5;818:278-286.

纯度：≥98%

CAS：763926-98-3