Pimobendan (hydrochloride) (UD-CG115 (hydrochloride)) is a selective inhibitor of PDE3 with IC50 of 0.32 μM. References: Kajimoto K, et al. Contribution of phosphodiesterase isozymes to the regulation of the L-type calcium current in human cardiac myocytes. Br J Pharmacol. 1997 Aug;121(8):1549-56.
[2]. Iwasaki A, et al. Pimobendan inhibits the production of proinflammatory cytokines and gene expression of inducible nitric oxide synthase in a murine model of viral myocarditis. J Am Coll Cardiol. 1999 Apr;33(5):1400-7.
纯度:≥98%
CAS:77469-98-8