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BMS303141
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
BMS303141图片
CAS NO:943962-47-8
包装与价格:
包装价格(元)
10mg电议
25mg电议
50mg电议
100mg电议

产品名称
BMS 303141, BMS-303141
产品介绍

生物活性

BMS303141是有效的ATP柠檬酸裂解酶(ACL)抑制剂。BMS303141以8μM的IC50抑制HepG2细胞中的脂质合成,并在鼠类高脂血症模型中降低血浆甘油三酸酯。

化学数据

目录号A13807
作用机制Inhibitor (抑制剂)
M. Wt424.3
FormulaC19H15Cl2NO4S
Purity>99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No.943962-47-8
SynonymsBMS 303141, BMS-303141
SMILESCOC1=C(C=C(C=C1)C2=CC=CC=C2)NS(=O)(=O)C3=CC(=CC(=C3O)Cl)Cl

溶解度

In vitroDMSO73 mg/mL (172.04 mM)
WaterInsoluble
EthanolInsoluble
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

储备液配制

Concentration / Solvent Volume / Mass1 mg5 mg10 mg
0.1 mM23.57 mL117.84 mL235.68 mL
0.5 mM4.71 mL23.57 mL47.14 mL
1 mM2.36 mL11.78 mL23.57 mL
5 mM0.47 mL2.36 mL4.71 mL

*The above data is based on the productmolecular weight 424.3. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.