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ISRIB(trans-isomer)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
ISRIB(trans-isomer)图片
包装与价格:
包装价格(元)
10mg电议
25mg电议
50mg电议
100mg电议

产品介绍

生物活性

ISRIB (trans-isomer)是一种有效的选择性小分子PERK信号抑制剂(IC50?5 nM),可以有效逆转eIF2α磷酸化的作用。

化学数据

目录号A13816
作用机制Inhibitor (抑制剂)
M. Wt451.34
FormulaC22H24Cl2N2O4
Purity>99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

SMILESO=C(N[C@@H]1CC[C@@H](NC(COC2=CC=C(Cl)C=C2)=O)CC1)COC3=CC=C(Cl)C=C3

储备液配制

Concentration / Solvent Volume / Mass1 mg5 mg10 mg
0.1 mM22.16 mL110.78 mL221.56 mL
0.5 mM4.43 mL22.16 mL44.31 mL
1 mM2.22 mL11.08 mL22.16 mL
5 mM0.44 mL2.22 mL4.43 mL

*The above data is based on the productmolecular weight 451.34. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.